Two sample MR report
NRP2_Alveolar Macrophages against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 6 | 0.2015482 | 0.1539161 | 0.2605252 |
| Weighted median | 6 | 0.0354100 | 0.0140678 | 0.0118327 |
| Inverse variance weighted | 6 | 0.0308704 | 0.0113856 | 0.0067011 |
| Simple mode | 6 | 0.0414576 | 0.0200223 | 0.0931712 |
| Weighted mode | 6 | 0.0416320 | 0.0208507 | 0.1023738 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.7052492 | 4 | 0.9506800 |
| Inverse variance weighted | 1.9416778 | 5 | 0.8571548 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.1467394 | 0.1319661 | 0.3284845 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0002367 | 0 | TRUE | 0.1438877 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
